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Noordine, M.-L

Cross-sectional studies have shown that plasma and tissue glutathione concentrations decrease by approximately 10-15% per decade after age 45, and this decline is accelerated in conditions associated with chronic oxidative stress, including type 2 diabetes, cardiovascular disease, neurodegenerative diseases, HIV/AIDS, chronic liver disease, and chronic obstructive pulmonary disease (COPD) [2][3][10][11]

Acknowledgements The authors acknowledge Mohammed Bin Rashid University of Medicine and Health Sciences (MBRU), Al Jalila Foundation, and University of Sharjah (UOS)

In fact, GFP is extremely stable against various denaturation mechanisms and also readily renatures, especially above neutral pH [28]