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f , Analysis of protein synthesis in MYCN -amplified IMR5/75 cells (24 h) after low levels or complete depletion of Cys 2 , methionine (Met) or glutamine (Gln) in the culture medium ( n = 3 samples, experiment replicated 3 times)

It is easy for technicains to inspect the working condition of the cooling tower.Technicians can enter into the cooling tower during operation time 3

Consistently, cystine supplementation alone was sufficient to sustain intracellular GSH in the absence of other amino acids (Fig

Deducing from these results, leukemic transformation as a result of iron overload is a valid hypothesis but data are still ambiguous and more prospective trials are required