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Among the most prominently affected pathways were pyrimidine metabolism, purine metabolism, and alanine, aspartate, and glutamate metabolism, highlighting widespread perturbation of nucleotide biosynthesis and amino acidlinked metabolic flux following DHODH inhibition

Autophagy 18 (3), 643660

Centered around an inorganic core, organic-inorganic composite nanomaterials integrate multiple antimicrobial mechanisms from both material types to produce synergistic antimicrobial effects

Increased levels of iron have been confirmed in the PD midbrain, which in turn results in iron-induced oxidative stress and neurodegeneration (Chinta and Andresen 2008)