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Monitor patients undergoing these procedures for signs and symptoms of neurologic impairment such as midline back pain, sensory and motor deficits (numbness, tingling, or weakness in lower limbs), and bowel or bladder dysfunction

in total, 9 genera (including the unclassified group) and 38 metabolites met these criteria (metabolites published in Sampson et al., 2021 13 )

We calculated mean, standard deviation, median and range for continuous variables

According to Kaplan-Meier plots, patients with elevated levels of MMA had significantly increased cumulative incidence of cardiovascular and heart-specific death (Supplementary Fig