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Li Q, Liao J, Chen W, Zhang K, Li H, Ma F, et al

doi: 10.1021/acs.orglett.1c03112 Robinson, Samuel D., Kambanis, Lucas, Clayton, Daniel, Hinneburg, Hannes, Corcilius, Leo, Mueller, Alexander, Walker, Andrew A., Keramidas, Angelo, Kulkarni, Sameer S., Jones, Alun, Vetter, Irina, Thaysen-Andersen, Morten, Payne, Richard J., King, Glenn F

Pollard and Pomfrett specifically noted no tolerance induction in their work, and the older European clinical data on chronic insomnia models doesnt describe tolerance development either