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Heart failure with preserved ejection fraction (HFpEF) accounts for approximately half of all heart failure cases, with patients bearing a high symptomatic burden and physical limitations that impact their daily lives

Furthermore, glutathione is involved in the regulation of hormonal balance, including the synthesis and metabolism of estrogen and progesterone, which are critical for menstrual cycle regulation and embryo implantation

In good agreement with this finding, our analysis of the selected transcripts characterizing thiamine-dependent metabolism, shows an overall increase in the transcripts for the related proteins (Figures 4, 5)

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