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Description

single-cell RNA sequencing of human cerebrospinal fluid (CSF) microglia and myeloid cells

The suspension was incubated at 37 C for 30 minutes, homogenized by vortexing for 10 seconds, and centrifuged at 14,000g for 10 minutes

However, until such interventions become available, alternative pharmacological approaches must be explored, considering their associated risks

Interventions aimed directly at increasing sGC activity independently of its redox state (also known as sGC agonists, namely sGC stimulators and sGC activators) could show therapeutic potential under those circumstances