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First, reduction of localized oxygen concentrations so that oxidation by molecular oxygen is less likely to occur

The anti-cancer mechanisms of berberine: a review

Furthermore, in a clinical trial (NCT04739618), researchers explored the potential benefits of nonablative cryosurgical freezing-induced necroptosis followed by immunotherapeutic drug injection in metastatic solid tumors

hAECs specifically differentiate into GCs, as confirmed by the presence of human-specific nuclear antigen and human follicle-stimulating hormone receptor expression in recipient ovaries (Zhao et al