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Lancet Respirat Med

Ubiquitination leads to covalent attachment of Ub, typically to lysine residues on target proteins, which eventually leads to monoubiquitination or polyubiquitination 120

It is said that you should not have more than one injection every three months as too many injections increase the risk of side effects, such as avascular necrosis, which is the lack of blood flow to a part of the bone that causes it to collapse

The reference treatment is embolization: without anesthesia, without surgery, without pain, without scarring, it is the most comfortable treatment (comparable to a CT scan) and the most reliable (90-95% success rate) for the patient