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10.1016/j.abb.2008.06.004 Arch Biochem Biophys

As discussed above, energy metabolism dysfunction is a characteristic sign of ALS disease and defects in skeletal muscle energy metabolism deeply contribute to disease progression (Dupuis et al., 2011)

Discussion Michael addition reaction has been widely applied in organic synthesis and bioconjugation to build carboncarbon and carbonheteroatom bonds based on its forward reaction