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Given that the authors found that the top 10 key target proteins were markedly enriched in the cellular senescence pathways, they further used molecular docking to verify that the cellular senescence marker proteins p53, p21 and p16 are potential binding targets of AS-IV

4.1.2 Function of curcumin in AD The strategies of curcumin to address AD mainly include the inhibition of A aggregation and tau hyperphosphorylation, anti-oxidation, anti-inflammation and brain-gut axis regulation (Pei et al., 2024

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Additionally, excessive copper can disturb intracellular calcium ion homeostasis, which is critical for noemal ER function