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WP is particularly rich in the branched-chain amino acids valine, leucine, and isoleucine, which play a crucial role in tissue growth and repair (Brestensk et al., 2015)

As newly identified metal ion-dependent programmed cell death modalities, ferroptosis and cuproptosis play critical roles in tumor metabolism, immune microenvironment remodeling, and therapeutic resistance, representing emerging research foci in OSCC

Vagal and enteric release of acetylcholine is also responsible for digestive enzyme secretion, hepatic bile release , and grastic acid secretion in the stomach

According to the review, nano-co-delivery of natural products with chemotherapeutic agents is expected to be the basis of new tumor therapeutic strategies that facilitate the development and translation of anticancer drugs (256)