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The peptide has also shown that it is a candidate in the treatment of periodontal disease when it was given to a rodent test subject that had periodontitis

The thyroid contains an antioxidant enzyme system that, under healthy conditions, provides an antioxidant shield to prevent destruction caused by superoxide free radicals (da Silva et al

Without copper coordination, the tripeptide shows much lower potency in fibroblast-stimulating assays, which suggests the metal complex is necessary to fully engage receptors or targets