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In most cases, a session lasts between 30 and 60 minutes

doi: 10.1016/j.immuni.2015.09.007 231 DuschaAGiseviusBHirschbergSYissacharNStanglGIEilersEet al

When external stimuli excite the vagus nerve, the nerve terminals produce the anti-inflammatory parasympathetic neurotransmitter acetylcholine (ACh), which activates the 7 nicotinic acetylcholine receptors (7nAChR) on monocytes and macrophages