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1 Islamic Azad University, Rasht Branch, Department of Animal Science, Rasht, Iran, 2 Islamic Azad University, Rasht Branch, Department of Veterinary Science, Rasht, Iran, 3 Vetmeduni Wien, Vienna, Austria, 4 Polytechnic Institute, Agricultural School, Department of Zootechnic Sciences, Animal Reproduction Laboratory, Coimbra, Portugal, 5 CERNAS- Centre for Studies on Natural Resources, Environment and Society, Polytechnic Institute, Coimbra, Portugal

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Viral nsp12 could alter AA metabolism (especially of the branchedchain amino acids , BCAA), while nsp12, nsp7 , and nsp8 interactions with electron transport chain (ETC) and ribosomal proteins could potentially dysregulate mitochondrial respiration 39

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