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Benefits of low MAO-A: With a positive childhood and good parenting, low MAO-A levels are linked to a decreased risk of aggression in both men and women.[ref] While parental acceptance and involvement benefit all teen boys, a study showed that teen boys with higher MAO-A levels exhibited even higher sensitivity toward parental involvement.[ref] Interestingly, women with the warrior gene version of MAOA are at a lower risk of ADHD.[ref] COMT and MAOA Interaction: The COMT enzyme also breaks down catecholamines (dopamine, norepinephrine, and epinephrine)

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28 Salmond and Allread capture the grim situation of the opioid epidemic in their 2019 paper on the subject, explaining that OUD is the deadliest drug crisis in American history