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The primary efficacy measures were the patients survival rate (time to death or full ventilation support) and their changes in functional ability (measured by ALSFRS-R scores)

If you develop signs of high cortisol like central weight gain despite overall weight loss, morning headaches, or mood disturbances, testing cortisol through saliva or 24-hour urine collection may be appropriate

Side effects and safety warnings Patients taking semaglutide report experiencing gastrointestinal-related side effects, including vomiting, nausea, diarrhea, constipation, headache, and fatigue