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In another trial, 41 women with mild to advanced photodamage applied GHK-Cu eye cream for three months and saw reduced lines and wrinkles, improved skin density, and increased skin thickness better than both placebo and vitamin K cream.3 Similarly, in a pilot study investigating copper tripeptide topicals for aged skin, experts found that they increased skin thickness and elasticity, improved hydration, and boosted collagen synthesis.3 Hair growth In a review from 2023, experts explained that GHK-Cu may promote hair growth in a few different ways

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The extent to which vitamin B 12 deficiency contributes to the symptoms of these patients is not clearly illustrated in the studies, although the patients mean baseline vitamin B 12 levels were within normal range in two studies.(10,11) Furthermore, as no serious adverse events were reported in most of the studies, no extended follow-up of patients to assess for harm due to supplementation was conducted