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This activation alleviates the damage to the alveolar capillary barrier and maintains the barrier function of pulmonary microvascular endothelial cells, suggesting that the SIRT1/p53 axis plays a crucial role in regulating ferroptosis in ALI ( 3.4 Heart diseases Bioinformatics analysis has identified SIRT1 as a key gene associated with myocardial infarction, with its role in ferroptosis being particularly significant ( + and prostaglandin-endoperoxide synthase 2 (PTGS2) levels, decrease the apoptosis rate, and upregulate GPX4 and ferritin levels by activating the SIRT1/p53/SLC7A11 signaling pathway

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Repeat: 30 days on, 30 days off, repeat the structure