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Increases in PDK4 are associated with perturbation of mitochondria-associated membranes and mitochondrial quality control, which are emerging as a central mechanism in the pathogenesis of metabolic disease-associated muscle atrophy

CETP plays a crucial role in HDL metabolism by facilitating the transfer of cholesteryl esters from HDL to apolipoprotein (apo) B-containing lipoproteins in exchange for TG

A soft Lewis acid, it favors tetrahedral coordination with soft bases such as hydrides, alkyl groups, cyanide, phosphines, and thiols from cysteine and thioether bonds with methionine (Crichton and Pierre, 2001)

These findings suggest that suppressing Nrf2 signalling may be critical for the ECM remodelling produced by mechanical damage (Li et al