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Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies

Research from the American Journal of Physiology (2016) demonstrated that glycine maintains Akt-mTOR-FOXO1 signaling, the anabolic cascade that drives muscle protein synthesis, while simultaneously suppressing TLR4 and NOD2 signaling pathways associated with inflammation-driven muscle breakdown