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10.1016/j.etap.2014.08.018 8 BaiX.MaQ.LiQ.YinM.XinY.ZhenD.et al (2023)

While challenges persist regarding incomplete understanding of regulatory networks and nanocarrier biosafety issues, this review not only provides a theoretical framework for comprehending ferroptosis-mediated anti-GBM mechanisms but also outlines future research directions, including in-depth dissection of ferroptosis signaling hubs, development of intelligent nano-delivery systems, and establishment of preclinical safety evaluation protocols

L.Le GallG.BrancaJ

This metabolic imbalance contributes to increased lipid peroxidation, as indicated by high malondialdehyde (MDA) levels ( These mitochondrial impairments not only compromise energy production but also act as pro-inflammatory stimuli, promoting chronic neuroinflammation through dysregulated mitochondrial signaling and innate immune response