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In such a study with a cohort of ME/CFS patients compared to HC, a metabolomic analysis revealed in the ME/CFS patients, metabolic disruptions in lipid-related as well as energy-related pathways (266), reinforcing the relevance of the mitochondrial dysfunction hypothesis

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The application of high-throughput technologies has further advanced our understanding of the molecular pathophysiology of endometriosis (Meola et al., 2010)