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Eur J Clin Invest 42:637648 Tian YF, He CT, Chen YT, Hsieh PS (2013) Lipoic acid suppresses portal endotoxemia-induced steatohepatitis and pancreatic inflammation in rats

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Furthermore, dihydroethidine (DHE) staining showed that the proportion of DHE-positive cells after OGD treatment was higher than that in the control group, suggesting that the level of reactive oxygen species (ROS) was increased (Figure 3G)

So heres some information about what toxins cause elevated liver enzymes in dogs Medications Drugs like phenytoin and phenobarbital prescribed for seizures, as well as any other drug, including heartworm medication and anti-inflammatory drugs, can result in abnormal liver enzymes, so if your dog is on any medication your vet should always consider whether that may be the cause