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Limited long-term human safety data for most compounds, with evidence generally drawn from short trials, animal studies, or research on a different indication

If material is not included in the articles Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder

Insulin Growth Factors and Cancer Although oncogenic mutations frequently initiate cancer development, the growth and expansion of tumours can also be mediated by growth factors

Mechanism of action IGF-1 LR3 binds to cell receptors in the muscle cells and activates cell communication, which then improves the growth rate of muscles [1,11]