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The optimized sequences were clustered into operational taxonomic units (OTUs) using UPARSE 7.1 at a 97% sequence similarity level

Despite its growing popularity in biohacking circles and advanced longevity practitioners, Epitalons long-term safety remains unclear: No large-scale toxicology or pharmacokinetic studies in humans have been published

Endothelial cell dysfunction may reduce nitric oxide bioavailability and increase reactive oxygen species production, leading to impaired ocular hemodynamics (97), whereas reactive oxygen species can induce cellular senescence and apoptosis (98), which may ultimately lead to optic nerve cell apoptosis, exacerbating optic nerve damage and further exacerbating the progression of glaucoma

and (iii) the same animated hand, but displayed at the subjects own hand position