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10.3389/fmolb.2020.602282 107 SunG

In summary, our approach demonstrates the feasibility of using peptide-mediated targeting to achieve cell-specific ionotropic receptor modulation and highlights the therapeutic potential of unimolecular mixed GLP-1 receptor agonism and NMDA receptor antagonism for safe and effective obesity treatment

At Phylum level, samples from Apc +/Min /Stard7 IEC mice were enriched in Bacteroidota ( P = 0.03) and showed lower levels of Firmicutes ( P = 0.05) (Fig