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Moreover, this study revealed for the first time that the downregulation of the mitochondrial biogenesis coactivator PGC-1 and its downstream nuclear factors are linked to mtDNA content in high-fat diet-induced obesity, muscle density loss, mitochondrial and myocardial contractile dysfunction, ROS accumulation, and intracellular Ca 2+ signaling

Jeongs group firstly found the up-regulation of TRPM7 protein in PILO-treated epileptic rats [54]

Not only does preserving lean muscle deliver metabolic benefits, but it also helps keep us mobile and stable

Differentially expressed angiogenic genes in diabetic erectile tissue results from a microarray screening