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doi: 10.1080/21541248.2016.1240495 299 WeihlC

Illustratively, the assessment included the morphologic features of mucosal injury (i.e., different grades of epithelial lifting, villi denudation, and necrosis), inflammation (i.e., focal to diffuse, according to lamina propria infiltration or subendothelial infiltration), and hyperemia/hemorrhage (i.e., focal to diffuse, according to lamina propria or subendothelial localization)

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These results indicate that PSPH-amplified or mutant ser/gly high synthesis GBMs are strongly dependent on their superior physiological mitochondrial function, which is effectively targeted by sertraline plus chloroquine