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Withaferin A modulates the Spindle Assembly Checkpoint by degradation of Mad2Cdc20 complex in colorectal cancer cell lines

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(After subjecting Tri-Fortify to 104F and 75% humidity for 90 consecutive days, it still exceeded label claims)

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Disruption of apoptotic mechanisms can lead to drug resistance, particularly in cases where chemotherapy resistance is related to defects in cell death mechanisms [3]