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Assessing the tissue ET concentrations of control mice, we found that of the 10 tissues measured (expressed in mass per wet weight of tissue standard error), liver had the highest amount of ET (80.65 4.14 ng/mg), followed by whole blood (58.99 2.05 ng/l blood), spleen (36.45 3.72 ng/mg), kidney (27.61 2.61 ng/mg), lung (19.56 1.46 ng/mg), heart (12.09 1.20 ng/mg), small intestine (7.23 0.86 ng/mg), eye (5.40 0.29 ng/mg), large intestine (4.37 0.93 ng/mg) and brain (3.73 0.59 ng/mg) (Fig