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10.1016/j.spinee.2012.12.002 33 KamataniT.HagizawaH.YarimitsuS.MoriokaM.KoyamatsuS.SugimotoM.et al (2022)

For example, the TUNEL assay, which detects DNA strand breaks [47], stains necrotic cells during APAP hepatotoxicity [42, 48]

The PM proton pumps expel H + from the cells and maintain the PM potential gradient necessary for the Na + /H + antiporter (SOS1) to efficiently exchange extracellular H + with intracellular Na +