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GH also has a protective effect on the CNS, as indicated by its beneficial effects in patients with spinal cord injury Growth hormone injections have shown great potential in adults who suffer from mild cognitive impairment: The intent-to-treat analysis indicated a favorable effect of GHRH on cognition (P=.03), which was comparable in adults with MCI [mild cognitive impairment] and healthy older adults.The completer analysis showed a similar pattern, with a more robust GHRH effect (P=.002)

In a subsequent RCT of the same group, a lower IGF-1 dosage (50 g/kg twice daily) and intermittent treatment protocol, with cycles of 4-day treatment interrupted by 3 days off treatment, in patients with stage 5 CKD (GFR 615 ml/min/1.73 m 2 ) was used [178]

Use one vial of tesamorelin and one of ipamorelin when you want to adjust each compound on its own

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