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Upregulation of tissue factor on monocytes and other cells or endothelial injury exposing tissue factor would also trigger DIC in dogs with IMHA by activating factor VII (Kidd et al 2015)

[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Kim G.B., Aragon-Sanabria V., Randolph L., Jiang H., Reynolds J.A., Webb B.S., et al

In their study, Das et al

Furthermore, certain diseases such as fractures, osteoarthritis, and osteomyelitis, are characterized by localized pH alternations, thereby presenting significant application prospects for pH-responsive materials