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Ascorbate synthesis and accumulation are particularly sensitive to the changing light environ- ment, particularly red/far-red ratios, effects that are in line with the direct interactions between the ascorbate pool and the photosynthetic and respiratory electron transport chains (Bartoli et al., 2006, 2009)

The PCR products were purified using ExoSAP-IT (Thermo Fisher Scientific) before sequencing

Pyruvate can be obtained from two sources: glucose-derived pyruvate from the cytosol and the ME2-catalyzed conversion of mitochondrial L-malate to pyruvate

FAC-induced lipid peroxidation accumulation in primary epithelial cells was measured by a fluorescent lipid probe, C11-BODIPY, and this increase was suppressed by ferroptosis inhibitors, ferrostatin-1 and liproxstatin-1 (Fig