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Description

All animals were kept in temperature- and humidity-controlled rooms under a 12 h/12 h light/dark cycle

The present results demonstrated that Klotho protein significantly contributed to inhibition of the IGF1R/PI3K/AKT signalling during heart IRI

Guha, N., Cowan, D.A., Sonksen, P.H

Most proinflammatory cytokines such as IL-6, IL-1, TNF-, IL-8, and IFN as well as some anti-inflammatory mediators including -aminoisobutyric acid, A20 enzyme, and EPO have been shown to impair adipogenesis, leading to adipocyte hypertrophy, ectopic fat accumulation, and increased risk of IR and T2DM