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The number of iron replacements in the PG-DTR group was significantly lower than that in the TG group (p=0.002) (Fig

Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from nanopore sequencing

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Later, the multiple hit hypothesis was raised by Buzzetti et al., in which it was proposed that multiple insults (including insulin resistance, inflammatory cytokines, nutritional imbalance, gut microbiota, genetic and epigenetic factors) acted together in contributing to the development of NAFLD in genetically predisposed subjects [5]