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Meanwhile, for many years now, scientists have studied the effects of low-dose naltrexone (LDN) on the gut epithelial barrier in treatment-resistant Ulcerative colitis patients

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

Nat Rev Endocrinol (2019) 15:32338

A future need for this AOP is a vigorous and thorough experiment model system to evaluate dose-response relationships, conentration-response relationships and exposure-effect relationships within the framework of this AOP