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Twenty-two patients were enrolled in the study and were assigned to one of five cohorts receiving a single IV infusion of pegadricase (0.1, 0.2, 0.4, 0.8, or 1.2 mg/kg) (Supplementary Figure 1)

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Apoe + macrophages and T cell types are critical for the reconstitution of pulmonary immunity In addition to structural restoration, the reconstitution of immunity is also an important step in organ regeneration such that we analyzed macrophages and T cells