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10.1007/s00284-016-1083-z Summary Keywords glutathione reductase, Acidithiobacillus caldus , heavy metal tolerance, bioleaching, antioxidation Citation Shi Y, Wu W, Yang Y, Liu X, Lin J, Liu X, Lin J and Pang X (2023) Gene knockout of glutathione reductase results in increased sensitivity to heavy metals in Acidithiobacillus caldus