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According to our previous research, in RA patients screened by proteomic analysis, the only differentially expressed protein (DEPs) that was significantly changed between the non-responsors and responsors group after combination treatment of MTX + leflunomide (LEF) + infliximab (IFX) was Tf (86), which could be a clue that biological agents regulate ferroptosis

Generalized polarization (GP) values represent membrane rigidity (higher value, red) or fluidity (lower value, blue)

If these test results are normal, then MdDS can be considered a diagnosis through exclusion 28

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