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Finally, we validated our findings in a preclinical CLL model (i.e., E-TCL1 transgenic mice), which recapitulates key features of aggressive CLL and is widely considered to reflect the biology of CLL with unmutated IGHV (U-CLL)

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She said that although topical hydroquinone (a product you can only get with a prescription) is generally the gold standard when it comes to treating pigmentation concerns, she recommends looking for a few specific ingredients such as niacinamide, vitamin C, and tranexamic acid of which this product has all three