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None of the combination-specific risks have been characterized in a human trial because that trial does not exist

Lipton SA (2006) Paradigm shift in neuroprotection by NMDA receptor blockade: Memantine and beyond

Human trials are needed to confirm its safety and effectiveness before widespread clinical use

HGF heptocyte growth factor MSP macrophage stimulating protein the AnglV analog Norleual which is a potent inhibitor of the HGF/Met system, was shown to bind to HGF and block its dimerization (Kawas et al, 2011)