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These results warrant further study to determine factors that may adversely affect survival in Black recipients and race mismatched transplants with PSC, such as increased rates of rejection, recurrent PSC or other factors

BPC-157 reverses short bowel syndrome manifestations in animal models, promoting constant weight gain above preoperative values and increasing villus height, crypt depth, and muscle layer thickness in the remaining intestinal tissue

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CRISPR/Cas9-mediated gene editing Single guide RNA sequences targeting SLC27A5 and GSR were designed (Table S1) using the E-CRISP ( and cloned into the Cas9-expressing lentiviral vector CRISPRv2 (Prof