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Conclusions Botulinum toxin type A (BTX-A) has proven effective in reducing synkinesis and improving facial symmetry, especially when applied to both the affected and contralateral healthy side

In addition to the previously mentioned inhibitory mechanisms, hypoxia-inducible heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) promotes exosome packaging miRNA [341, 481]

Cyclosporine-induced liver dysfunction, although less common, can be managed by dose reduction or switching to alternative medications such as adalimumab, while antioxidant supplementation such as vitamin E and N-acetylcysteine has shown potential in mitigating oxidative liver damage (Ighani et al

PMID: 34447191