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This bond is also called an SS bond or sometimes a disulfide bridge and is usually derived from two thiol groups

TNF- in turn induces the actions of IL-6 (Selzner, et al., 2003), which is involved in steatohepatitis development by sensitizing the liver to injury and promoting apoptosis in hepatocytes (Braunersreuther et al., 2012)

Moreover, multi-targeted combination therapies that integrate synthetic and natural compounds could yield superior outcomes compared to single-target treatments