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Introduction Glutathione S -transferases (GSTs) are a family of enzymes that conjugate reduced glutathione (GSH) to target molecules in the phase II detoxification of xenobiotic metabolism ( Here we examined the mechanisms of how GSTM1 regulates astrocyte transcriptional program in response to pro-inflammatory signaling and further addressed the impact of GSTM1 loss-of-function on neurons during acute brain inflammation following a systemic injection of lipopolysaccharides (LPS)

After weight loss, all groups showed decrease in irisin level

doi: 10.1111/j.1398-9995.2009.01969.x 89 BoehmeSASullivanSKCrowePDSantosMConlonPJSriramaraoPet al

Heterogeneous blood-tumor-barrier permeability determines drug efficacy in experimental brain metastases of breast cancer