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The combination of the NIT criteria was able to identify the patients with accurate histological features with a sensitivity of 39.6% and specificity of 67.8% (positive predictive value: 39.6%, negative predictive value: 67.8%)

doi: 10.1038/nrendo.2017.90 91 LiuZGanLZhangTRenQSunC

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Such combinations are involved in the stabilization of certain proteins, protecting them against toxic oxidation processes caused by adverse environmental conditions (e.g., selenium and acid stress)