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Elderly humans, for instance, exhibit 94.6% lower glutathione levels and significantly reduced synthesis rates compared to younger adults

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A randomized controlled trial (RCT) demonstrated that after 6 months of supplementation with 1.2 g/d of EPA + DHA for patients with knee OA, the WOMAC pain score decreased by 23% ( p = 0.02), and the synovial inflammation assessed by MRI was relieved (42)

Also helpful was the coordination of federal health research at the level of the Assistant Secretary of Health and Human Services (HHS) for Preparedness and Response, an office that had been formed in 2006 as a result of problems in responding to Hurricane Katrina