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For end point dissection, mice were anaesthetized with isoflurane followed by retroorbital bleeding, PBS perfusion and/or tissue collection

W., Willett, W

Because cognitive impairment is one of the core symptoms of depression, this finding suggests that disruptions in brain iron homeostasis during adolescence may increase the risk of developing depression by affecting cognitive development

Ketone bodies are products generated in the liver during fatty acid breakdown and can serve as alternative energy sources for the brain and other tissues (19, 54)